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Qiao-Hong Chen

Principal Investigator

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Stan Iridio Gomez, M.S.

Undergraduate Student, 2020-2022

Graduate Student, 2022-2025            Lecturer, 2025-

Publications

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  • "Tetracyclic Bis-Piperidine Alkaloids: Structures, Bioinspired Synthesis, Synthesis, and Bioactivities", Stan Iridio Gómez, Esveidy Isabel Oceguera Nava, Abbas Dadawalla, Dennis Ashong, Guanglin Chen, Qiao-Hong Chen*, Molecules 30(14): 2907 (2025).

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Daniel Hidalgo

Graduate Student, 2024-

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Eva Chen

Undergraduate

Publications

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  • "Core Structure-Activity Relationship Studies of 5,7,20-O-Trimethylsilybins in Prostate Cancer Cell Models", SitongWu, Guanglin Chen, Eva Y. Chen, Leyla S. Farshidpour, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Pharmaceuticals, 16: 531 (2023).

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Danya Sumrein

Undergraduate, 2024-

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Vang Yang

Undergraduate, 2024-

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Talia Nvart Solak

Undergraduate Student, 2025-

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Sabrina Luna Olmedo

Undergraduate, 2025-

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Jacob Rojas

Undergraduate Student, 2025-

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Elizabeth Herren
Graduate Student, 2023-

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Riddhi Chatrola
Graduate Student, 2024-

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Gurmannat Chalotra
Undergraduate Student, 2023-

 

2025 Glenn Nagel Undergraduate Research Award.

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Eakmjyot Bual
Undergraduate Student, 2024-

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Jack Tyler Lewis
Undergraduate, 2025-

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Padouachi Heu
Undergraduate Student, 2023-

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Luciano Noguera
Undergraduate Student, 2024-

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Isabelle Capuias
Undergraduate, 2024-

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Dayeon Moon
Undergraduate, 2024-

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Eliza Basaula
High School Student, 2025-

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Former Members

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Dr. Rubing Wang

Post-Doctoral Research Associate(2013-2015)

PhD., Shanghai Jiao Tong University, China 

Current position: Full Professor of Peking Union Medical College Pharmaceutical Institute             

Publications

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  • "Optimized synthesis and antiproliferative activity of desTHPdactylolides", Guanglin Chen, Rubing Wang, Bao Vue, Manee Patanapongpibul, Qiang Zhang, Shilong Zheng, Guangdi Wang, James D. White, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 26(12): 3515-3520 (2018).

  • "Structure-activity relationship studies of 1,7-diheteroarylhepta-1,4,6-trien-3-ones with two different terminal rings in prostate epithelial cell models", Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen, Cristian Sarabia, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 133: 208-226 (2017).

  • "Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies", Xiaojie Zhang, Shanchun Guo, Chengsheng Chen, German Ruiz Perez, Changde Zhang, Manee Patanapongpibul, Nithya Subrahmanyam, Rubing Wang, Joshua Keith, Guanglin Chen, Yan Dong, Qiang Zhang, Qiu Zhong, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 137: 263-279 (2017).

  • "Design, Synthesis, and Biological Evaluation of 1,9-Diheteroarylnona-1,3,6,8-tetraen-5-ones as a New Class of Anti-Prostate Cancer Agents", Xiaojie Zhang, Rubing Wang, German R Perez, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 24(19): 4692-4700 (2016).

  • "Synthesis and evaluation of 1,7-diheteroarylhepta-1,4,6-trien-3-ones as curcumin-based anti-cancer agents", Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen, Qiu Zhong, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 110: 164-180 (2016).

  • "Effects of curcumin-based compounds on proliferation and cell death in cervical cancer cells", Xiaojie Zhang, Rubing Wang, Guanglin Chen, Laurent Dejean*, and Qiao-Hong Chen*, Anticancer Research, 35(10): 5293-5298 (2015).

  • "A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: design, synthesis, and anti-proliferative evaluation", Qiao-Hong Chen*, Kevin Yu, Xiaojie Zhang, Guanglin Chen, Andrew Hoover, Francisco Leon, Rubing Wang, Nithya Subrahmanyam, Ermias A Mekuria, Liva H Rakotondraibe, Bioorganic & Medicinal Chemistry Letters, 25(20): 4553-4556 (2015).

  • "Structure-Activity relationship and pharmacokinetic studies of 1,5-diheteroarylpenta -1,4-dien-3-ones: a class of promising curcumin-based anti-cancer agents", Rubing Wang, Chengsheng Chen, Xiaojie Zhang, Changde Zhang, Qiu Zhong, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Journal of Medicinal Chemistry, 58 (11), 4713–4726 (2015).

  • "Design, Synthesis, and Evaluation of Genistein Analogues as Anti-cancer Agents", Pahoua Xiong, Rubing Wang, Xiaojie Zhang, Eduardo Dela Torre, Francisco Leon, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Anti-Cancer Agents in Medicinal Chemistry, 15(9): 1197-1203 (2015).

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Xiaojie(Jay) Zhang                                               

Master Graduate Student, 2013-2016                                                     

BS., Nanchang University, China

Ph.D., Oregon State University

Publications

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  • "O-Aminoalkyl-O-trimethyl-2,3-dehydrosilybins: Synthesis and in vitro effects towards prostate cancer cells", Bao Vue, Sheng Zhang, Andre Vignau, Guanglin Chen, Xiaojie Zhang, William Diaz, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Molecules, 23: 3142, (2018).

  • "Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies", Xiaojie Zhang, Shanchun Guo, Chengsheng Chen, German Ruiz Perez, Changde Zhang, Manee Patanapongpibul, Nithya Subrahmanyam, Rubing Wang, Joshua Keith, Guanglin Chen, Yan Dong, Qiang Zhang, Qiu Zhong, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 137: 263-279 (2017).

  • "Structure-activity relationship studies of 1,7-diheteroarylhepta-1,4,6-trien-3-ones with two different terminal rings in prostate epithelial cell models", Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen, Cristian Sarabia, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 133: 208-226 (2017).

  • "5- or/and 20-O-Alkyl-2,3-dehydrosilybins: Synthesis and biological profiles on prostate cancer cell models", Bao Vue, Xiaojie Zhang, Timmy Lee, Nandini Nair, Sheng Zhang, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 25(17): 4845-4854 (2017).

  • "Design, Synthesis, and Biological Evaluation of 1,9-Diheteroarylnona-1,3,6,8-tetraen-5-ones as a New Class of Anti-Prostate Cancer Agents", Xiaojie Zhang, Rubing Wang, German R Perez, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 24(19): 4692-4700 (2016).

  • "A new class of flavonol-based anti-prostate cancer agents: design, synthesis, and evaluation in cell models", Xiang Li, Guanglin Chen, Xiaojie Zhang, Qiang Zhang, Shilong Zheng, Guangdi Wang,  and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 26(17): 4241-4245 (2016).

  • "3-O-Alkyl-2,3-Dehydrosilibinins: Two Synthetic Approaches and in vitro Effects toward Prostate Cancer Cells", Sheng Zhang, Bao Vue, Michael Huang, Xiaojie Zhang, Timmy Lee, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang,  and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 26(14): 3226-3231 (2016).

  • Aerobic Decomposition of Trialkylquercetins: Structure Characterization and Antiproliferative Effect", Sami M.R. Al-Jabban, Xiaojie Zhang(co-first author), Guanglin Chen, Liva Harinantenaina Rakotondraibe, and Qiao-Hong Chen*, Natural Product Communications, 11: 465-468 (2016).

  • "Synthesis and evaluation of 1,7-diheteroarylhepta-1,4,6-trien-3-ones as curcumin-based anti-cancer agents", Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen, Qiu Zhong, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 110: 164-180 (2016).

  • "Silibinin Derivatives as Anti-Prostate Cancer Agents: Synthesis and Cell-Based Evaluations", Bao Vue, Sheng Zhang, Xiaojie Zhang, Konstantinos Parisis, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 109: 36-46 (2016).

  • "Effects of curcumin-based compounds on proliferation and cell death in cervical cancer cells", Xiaojie Zhang, Rubing Wang, Guanglin Chen, Laurent Dejean*, and Qiao-Hong Chen*, Anticancer Research, 35(10): 5293-5298 (2015).

  • "Synthesis and Anti-Proliferative Effects of Quercetin Derivatives", Sami M.R. Al-Jabban, Xiaojie Zhang, Guanglin Chen, Ermias Addo Mekuria, Liva Harinantenaina Rakotondraibe, and Qiao-Hong Chen*, Natural Product Communications, 10: 2113-2118 (2015).

  • "A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: design, synthesis, and anti-proliferative evaluation", Qiao-Hong Chen*, Kevin Yu, Xiaojie Zhang, Guanglin Chen, Andrew Hoover, Francisco Leon, Rubing Wang, Nithya Subrahmanyam, Ermias A Mekuria, Liva H Rakotondraibe, Bioorganic & Medicinal Chemistry Letters, 25(20): 4553-4556 (2015).

  • "Structure-Activity relationship and pharmacokinetic studies of 1,5-diheteroarylpenta -1,4-dien-3-ones: a class of promising curcumin-based anti-cancer agents", Rubing Wang, Chengsheng Chen, Xiaojie Zhang, Changde Zhang, Qiu Zhong, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Journal of Medicinal Chemistry,  58 (11), 4713–4726 (2015).

  • "Design, Synthesis, and Evaluation of Genistein Analogues as Anti-cancer Agents", Pahoua Xiong, Rubing Wang, Xiaojie Zhang, Eduardo Dela Torre, Francisco Leon, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Anti-Cancer Agents in Medicinal Chemistry, 15(9): 1197-1203 (2015).

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Xiang (Jimmy) Li

Master Graduate Student, 2015-2017

BS., University of Electronic Science and Technology of China

Ph.D., University of Florida

Publications

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  • "Structure-activity relationship and pharmacokinetic studies of 3--substitutedflavonols as anti-prostate cancer agents", Xiang Li, Changde Zhang, Shanchun Guo, Pravien Rajaram, Maizie Lee, Guanglin Chen, Ryan Fong, Aaron Gonzalez, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 157: 978-993 (2018).

  • "3-O-Substituted-3',4',5'-trimethoxyflavonols: synthesis and cell-based evaluation as anti-prostate cancer agents", Xiang Li, Maizie Lee, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 25(17): 4768-4777 (2017).

  • "A new class of flavonol-based anti-prostate cancer agents: design, synthesis, and evaluation in cell models", Xiang Li, Guanglin Chen, Xiaojie Zhang, Qiang Zhang, Shilong Zheng, Guangdi Wang,  and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 26(17): 4241-4245 (2016).

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Ziran Jiang
Master Graduate Student, 2018-2020
Ph.D., University of California, San Diego

Publications

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  • "23-O-Substituted-2,3-dehydrosilybins selectively suppress androgen receptor-positive LNCaP prostate cancer cell proliferation", Ziran Jiang, Arman Sekhon, Yogeshwari Oka, Guanglin Chen, Nagat Alrubati, Jasleen Kaur, Alexia Orozco, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Natural Product Communications, 15(5): 1-10 (2020).

  • "New zampanolide mimics: Design, synthesis, and antiproliferative evaluation", Guanglin Chen, Ziran Jiang, Qiang Zhang, Guangdi Wang, and Qiao-Hong Chen*, Molecules, 25(2), 362 (2020).

  • "Synthesis and antiproliferative evaluation of new zampanolide mimics", Guanglin Chen, Manee Patanapongpibul, Ziran Jiang, Qiang Zhang, Shilong Zheng, Guangdi Wang, James D. White, Qiao-Hong Chen*, Organic & Biomolecular Chemistry, 17: 3830-3844,(2019).

  • "Nitrogen-containing derivatives of tetramethylquercetin: synthesis and biological profiles in prostate cancer cell models", Pravien Rajaram, Ziran Jiang, Guanglin Chen, Alyssa Rivera, Alison Phasakda, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic Chemistry, 87: 227-239 (2019).

  • "An amide mimic of desTHPdactylolide: Total synthesis and antiproliferative evaluation", Guanglin Chen, Maricarmen Gonzalez, Ziran Jiang, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 40: 127970 (2021).

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  Maizie Lee                                    
  Undergraduate, 2016-2018
  Ph.D., Emory University       

Publications

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  • "Structure-activity relationship and pharmacokinetic studies of 3--substitutedflavonols as anti-prostate cancer agents", Xiang Li, Changde Zhang, Shanchun Guo, Pravien Rajaram, Maizie Lee, Guanglin Chen, Ryan Fong, Aaron Gonzalez, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 157: 978-993 (2018).
  • "3-O-Substituted-3',4',5'-trimethoxyflavonols: synthesis and cell-based evaluation as anti-prostate cancer agents", Xiang Li, Maizie Lee, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 25(17): 4768-4777 (2017).
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Pravien Rajaram
Master Graduate Student, 2018-2020
Ph.D., University of California, Merced

Publications

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  • "Second-generation androgen receptor antagonists as hormonal therapeutics for three forms of prostate cancer", Pravien Rajaram, Alyssa Rivera, Kevin Muthima, Nicholas Olveda, Hubert Muchalski*, and Qiao-Hong Chen*, Molecules, 25(10): 2448 (2020).

  • "Nitrogen-containing derivatives of tetramethylquercetin: synthesis and biological profiles in prostate cancer cell models", Pravien Rajaram, Ziran Jiang, Guanglin Chen, Alyssa Rivera, Alison Phasakda, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic Chemistry, 87: 227-239 (2019).

  • "Structure-activity relationship and pharmacokinetic studies of 3-O-substitutedflavonols as anti-prostate cancer agents", Xiang Li, Changde Zhang, Shanchun Guo, Pravien Rajaram, Maizie Lee, Guanglin Chen, Ryan Fong, Aaron Gonzalez, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 157: 978-993 (2018).

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Cristian Sarabia                                                            
Undergraduate Student (2014-2017)
Ph.D., University of California, Merced

Publications

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  • "Structure-activity relationship studies of 1,7-diheteroarylhepta-1,4,6-trien-3-ones with two different terminal rings in prostate epithelial cell models", Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen, Cristian Sarabia, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 133: 208-226 (2017).

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Jasmine Hang
Master Graduate Student, 2023-2025
Ph.D. Student at University of Wisconsin Madison

Publications

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  • "Synthesis and Biological Evaluation of Niclosamide PROTACs", Erick Munoz, Guanglin Chen, Ahamed Hossain, Sitong Wu, Esveidy Oceguera, Jasmine Hang, Tong Lee, Qiang Zhang, Guangdi Wang*, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 72: 128870 (2022).

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Jasleen Kaur
Undergraduate Student 2017-2020
M.D., California Health Sciences University

Publications

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  • "23-O-Substituted-2,3-dehydrosilybins selectively suppress androgen receptor-positive LNCaP prostate cancer cell proliferation", Ziran Jiang, Arman Sekhon, Yogeshwari Oka, Guanglin Chen, Nagat Alrubati, Jasleen Kaur, Alexia Orozco, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Natural Product Communications, 15(5): 1-10 (2020).

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Sami Aljabban
Master Graduate Student (2013-2015)
BS., University of California, Davis
MD, International American University, St Lucia

Publications

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  • Aerobic Decomposition of Trialkylquercetins: Structure Characterization and Antiproliferative Effect", Sami M.R. Al-Jabban, Xiaojie Zhang, Guanglin Chen, Liva Harinantenaina Rakotondraibe, and Qiao-Hong Chen*, Natural Product Communications, 11: 465-468 (2016).

  • "Synthesis and Anti-Proliferative Effects of Quercetin Derivatives", Sami M.R. Al-Jabban, Xiaojie Zhang, Guanglin Chen, Ermias Addo Mekuria, Liva Harinantenaina Rakotondraibe, and Qiao-Hong Chen*, Natural Product Communications, 10: 2113-2118 (2015).

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Shaur Herng Chong
Undergraduate, 2023-2025
Ph.D. Student at UC Santa Barbara

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Khamyl Cooksey
Undergraduate, 2020-2023
Ph.D. Student at UC Merced

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Keyara Piri
Undergraduate Student, 2021-2024
MD student at Johns Hopkins University

Publications

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  • "Tricyclic Diterpenoids Selectively Suppress Androgen Receptor-PositiveProstate Cancer Cells", Inderpal Sekhon, Guanglin Chen, Keyara Piri, Seiji Shinkawa, Dennis Ashong, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Molecules, 28(12): 4743 (2023).

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Arman Sekhon

Undergraduate Student (2018-2020)

DO Student, Burrell College of Osteopathic Medicine

Publications

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  • "23-O-Substituted-2,3-dehydrosilybins selectively suppress androgen receptor-positive LNCaP prostate cancer cell proliferation", Ziran Jiang, Arman Sekhon, Yogeshwari Oka, Guanglin Chen, Nagat Alrubati, Jasleen Kaur, Alexia Orozco, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Natural Product Communications, 15(5): 1-10 (2020).

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Celia Shepard

Undergraduate Student, 2019-2020

PharmD Student, University of the Pacific

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Aditya DwivediVisiting student (2019)

BS, University of California, Berkeley

MD Student, UC San Francisco

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Eduardo Delatorre

Undergraduate, 2014-2015

PharmD, University of California, San Francisco

Publications

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  • "Design, Synthesis, and Evaluation of Genistein Analogues as Anti-cancer Agents", Pahoua Xiong, Rubing Wang, Xiaojie Zhang, Eduardo Dela Torre, Francisco Leon, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Anti-Cancer Agents in Medicinal Chemistry, 15(9): 1197-1203 (2015).

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Rodolfo Gonzalez

Undergraduate 2015-2016

PharmD, UC San Francisco 

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Malia Simms

Undergraduate Student, 2023-2024

MD Student, Ross University

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Pahoua Xiong

Graduate Student (2012-2015)

Lecturer, Chemistry and Biochemistry, Fresno State

Publications

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  • "Design, Synthesis, and Evaluation of Genistein Analogues as Anti-cancer Agents", Pahoua Xiong, Rubing Wang, Xiaojie Zhang, Eduardo Dela Torre, Francisco Leon, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Anti-Cancer Agents in Medicinal Chemistry, 15(9): 1197-1203 (2015).

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Yogeshwari Oka

Undergraduate, 2018-2021

Publications

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  • "23-O-Substituted-2,3-dehydrosilybins selectively suppress androgen receptor-positive LNCaP prostate cancer cell proliferation", Ziran Jiang, Arman Sekhon, Yogeshwari Oka, Guanglin Chen, Nagat Alrubati, Jasleen Kaur, Alexia Orozco, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Natural Product Communications, 15(5): 1-10 (2020).

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Seiji Shinkawa

Undergraduate Student, 2022-2024

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David Dat Nguyen

Undergraduate, 2024-2005

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Mekai Barrientez

Undergraduate Student, 2024-2025

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Alexia Orozco

Undergraduate, 2019-2020

Publications

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  • "23-O-Substituted-2,3-dehydrosilybins selectively suppress androgen receptor-positive LNCaP prostate cancer cell proliferation", Ziran Jiang, Arman Sekhon, Yogeshwari Oka, Guanglin Chen, Nagat Alrubati, Jasleen Kaur, Alexia Orozco, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Natural Product Communications, 15(5): 1-10 (2020).

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German Ruiz

Undergraduate Student (2014-2017)

(Fresno State, Biology)

Publications

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  • "Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies", Xiaojie Zhang, Shanchun Guo, Chengsheng Chen, , Changde Zhang, Manee Patanapongpibul, Nithya Subrahmanyam, Rubing Wang, Joshua Keith, Guanglin Chen, Yan Dong, Qiang Zhang, Qiu Zhong, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 137: 263-279 (2017).

  • "Design, Synthesis, and Biological Evaluation of 1,9-Diheteroarylnona-1,3,6,8-tetraen-5-ones as a New Class of Anti-Prostate Cancer Agents", Xiaojie Zhang, Rubing Wang, German R Perez, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 24(19): 4692-4700 (2016).

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Alaa Al Teshi

Undergraduate, 2023-2024

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Rawan Almufleyhi

Undergraduate, 2020-2023

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Melina Renteria

Undergraduate, 2024

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Shareen Purewal

Undergraduate, 2020-2023

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Samuel Barron

Undergraduate Student, 2020-2021

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Brandy Ezenwugo                                  

Undergraduate, 2018                                                       

    

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Andre Vignau

Undergraduate Student (2016-2017)

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Ryan Fong

High School Student, 2016

Chemical Engineering Student at Purdue University

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William Diaz                                  

Graduate Student, 2019-2021

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Nickolas Callender

Graduate Student, 2024

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Aaron Gonzalez                                     

High School Student, 2016

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Francisco (Aaron) Leon

Undergraduate, 2014-2015

Publications

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  • "A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: design, synthesis, and anti-proliferative evaluation", Qiao-Hong Chen*, Kevin Yu, Xiaojie Zhang, Guanglin Chen, Andrew Hoover, Francisco Leon, Rubing Wang, Nithya Subrahmanyam, Ermias A Mekuria, Liva H Rakotondraibe, Bioorganic & Medicinal Chemistry Letters, 25(20): 4553-4556 (2015)

  • "Design, Synthesis, and Evaluation of Genistein Analogues as Anti-cancer Agents", Pahoua Xiong, Rubing Wang, Xiaojie Zhang, Eduardo Dela Torre, Francisco Leon, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Anti-Cancer Agents in Medicinal Chemistry, 15(9): 1197-1203 (2015).

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Erica Romo I

Undergraduate 2015-2016   

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Christina Stavropoulos

Undergraduate, 2015-2016

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Jayjoel Fernandezc                                   

Undergraduate Student 2013-2015

   

Publications

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  • "Design, synthesis, and evaluation of novel heteroaromatic analogs of curcumin as anti-cancer agents", Nawras Samaan, Qiu Zhong, Jayjoel Fermandez, Guanglin Chen, Ali M Hussain, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 75: 123-131 (2014)..

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Konstantinos Parisis

Undergraduate 2014-2015

High School Biology Teacher

Publications

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  • "Silibinin Derivatives as Anti-Prostate Cancer Agents: Synthesis and Cell-Based Evaluations", Bao Vue, Sheng Zhang, Xiaojie Zhang, Konstantinos Parisis, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 109: 36-46 (2016)

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Bao Vue, M.S
Lecturer 2014-2018
PhD., University of California, Davis

Publications

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  • "O-Aminoalkyl-O-trimethyl-2,3-dehydrosilybins: Synthesis and in vitro effects towards prostate cancer cells", Bao Vue, Sheng Zhang, Andre Vignau, Guanglin Chen, Xiaojie Zhang, William Diaz, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Molecules, 23: 3142, (2018).

  • “Optimized synthesis and antiproliferative activity of desTHPdactylolides", Guanglin Chen, Rubing Wang, Bao Vue, Manee Patanapongpibul, Qiang Zhang, Shilong Zheng, Guangdi Wang, James D. White, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 26(12): 3515-3520 (2018).

  • 5- or/and 20-O-Alkyl-2,3-dehydrosilybins: Synthesis and biological profiles on prostate cancer cell models", Bao Vue, Xiaojie Zhang, Timmy Lee, Nandini Nair, Sheng Zhang, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 25(17): 4845-4854 (2017).

  • "The Potential of Flavonolignans in Prostate Cancer Management", Bao Vue, and Qiao-Hong Chen*, Current Medicinal Chemistry, 23(34): 3925-3950.

  • "3-O-Alkyl-2,3-Dehydrosilibinins: Two Synthetic Approaches and in vitro Effects toward Prostate Cancer Cells", Sheng Zhang, Bao Vue, Michael Huang, Xiaojie Zhang, Timmy Lee, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang,  and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 26(14): 3226-3231 (2016).

  • "Silibinin Derivatives as Anti-Prostate Cancer Agents: Synthesis and Cell-Based Evaluations", Bao Vue, Sheng Zhang, Xiaojie Zhang, Konstantinos Parisis, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 109: 36-46 (2016).

  • "Flavonoids with therapeutic potential in prostate cancer", Bao Vue, Sheng Zhang, and Qiao-Hong Chen*, Anti-Cancer Agents in Medicinal Chemistry, 16(10): 1205-1229, 2016.

  • "Synergistic Effects of Dietary Natural Products as Anti-Prostate Cancer Agents", Bao Vue, Sheng Zhang and Qiao-Hong Chen*, Natural Product Communications, 10: 2179-2188 (2015).

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Sheng Zhang
Master Graduate Student, 2014-2016
BS., East China University of Science and Technology, China
Ph.D., University of California, Irvine

Publications

​

  • "O-Aminoalkyl-O-trimethyl-2,3-dehydrosilybins: Synthesis and in vitro effects towards prostate cancer cells", Bao Vue, Sheng Zhang, Andre Vignau, Guanglin Chen, Xiaojie Zhang, William Diaz, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Molecules, 23: 3142, (2018).

  • "5- or/and 20-O-Alkyl-2,3-dehydrosilybins: Synthesis and biological profiles on prostate cancer cell models", Bao Vue, Xiaojie Zhang, Timmy Lee, Nandini Nair, Sheng Zhang, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 25(17): 4845-4854 (2017).

  • "3-O-Alkyl-2,3-Dehydrosilibinins: Two Synthetic Approaches and in vitro Effects toward Prostate Cancer Cells", Sheng Zhang, Bao Vue, Michael Huang, Xiaojie Zhang, Timmy Lee, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang,  and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 26(14): 3226-3231 (2016).

  • "Silibinin Derivatives as Anti-Prostate Cancer Agents: Synthesis and Cell-Based Evaluations", Bao Vue, Sheng Zhang, Xiaojie Zhang, Konstantinos Parisis, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 109: 36-46 (2016).

  • "Flavonoids with therapeutic potential in prostate cancer", Bao Vue, Sheng Zhang, and Qiao-Hong Chen*, Anti-Cancer Agents in Medicinal Chemistry, 16(10): 1205-1229, 2016.

  • "Synergistic Effects of Dietary Natural Products as Anti-Prostate Cancer Agents", Bao Vue, Sheng Zhang and Qiao-Hong Chen*, Natural Product Communications, 10: 2179-2188 (2015).

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Manee Patanapongpibul
Master Graduate Student, 2015-2018
BS., Mahidol University of Thailand
Ph.D., University of Groningen, The Netherlands

Publications

​

  • "Synthesis and antiproliferative evaluation of new zampanolide mimics", Guanglin Chen, Manee Patanapongpibul, Ziran Jiang, Qiang Zhang, Shilong Zheng, Guangdi Wang, James D. White, Qiao-Hong Chen*, Organic & Biomolecular Chemistry, DOI: 10.1039/C9OB00556K, (2019).

  • “Optimization of diarylpentadienones as chemotherapeutics for prostate cancer", Manee Patanapongpibul, Changde Zhang, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 26(16): 4751-4760 (2018).

  • “Optimized synthesis and antiproliferative activity of desTHPdactylolides", Guanglin Chen, Rubing Wang, Bao Vue, Manee Patanapongpibul, Qiang Zhang, Shilong Zheng, Guangdi Wang, James D. White, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 26(12): 3515-3520 (2018).

  • "Immune modulation of Asian folk herbal medicines and related chemical components for cancer management", Manee Patanapongpibul and Qiao-Hong Chen*, Current Medicinal Chemistry, DOI: 10.2174/0929867324666170705112644 (2017).

  • "Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies", Xiaojie Zhang, Shanchun Guo, Chengsheng Chen, German Ruiz Perez, Changde Zhang, Manee Patanapongpibul, Nithya Subrahmanyam, Rubing Wang, Joshua Keith, Guanglin Chen, Yan Dong, Qiang Zhang, Qiu Zhong, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 137: 263-279 (2017).

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Nithya Subramanyan

Master Graduate Student (2012-2015)

BS., University of California, Berkeley

Ph.D., University of Utah   

Publications

​

  • "Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies", Xiaojie Zhang, Shanchun Guo, Chengsheng Chen, German Ruiz Perez, Changde Zhang, Manee Patanapongpibul, Nithya Subrahmanyam, Rubing Wang, Joshua Keith, Guanglin Chen, Yan Dong, Qiang Zhang, Qiu Zhong, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 137: 263-279 (2017).

  • "A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: design, synthesis, and anti-proliferative evaluation", Qiao-Hong Chen*, Kevin Yu, Xiaojie Zhang, Guanglin Chen, Andrew Hoover, Francisco Leon, Rubing Wang, Nithya Subrahmanyam, Ermias A Mekuria, Liva H Rakotondraibe, Bioorganic & Medicinal Chemistry Letters, 25(20): 4553-4556 (2015).

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Chengsheng Chen

Master Graduate Student (2013-2015)

BS., Shanghai University, China

Ph.D., University of Connecticut

Publications

​

  • "Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies", Xiaojie Zhang, Shanchun Guo, Chengsheng Chen, German Ruiz Perez, Changde Zhang, Manee Patanapongpibul, Nithya Subrahmanyam, Rubing Wang, Joshua Keith, Guanglin Chen, Yan Dong, Qiang Zhang, Qiu Zhong, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 137: 263-279 (2017).

  • "Structure-activity relationship studies of 1,7-diheteroarylhepta-1,4,6-trien-3-ones with two different terminal rings in prostate epithelial cell models", Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen, Cristian Sarabia, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 133: 208-226 (2017).

  • "Synthesis and evaluation of 1,7-diheteroarylhepta-1,4,6-trien-3-ones as curcumin-based anti-cancer agents", Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen, Qiu Zhong, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 110: 164-180 (2016).

  • "Structure-Activity relationship and pharmacokinetic studies of 1,5-diheteroarylpenta -1,4-dien-3-ones: a class of promising curcumin-based anti-cancer agents", Rubing Wang, Chengsheng Chen, Xiaojie Zhang, Changde Zhang, Qiu Zhong, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Journal of Medicinal Chemistry, 58 (11), 4713–4726 (2015)..

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Esveidy Oceguera

Master Graduate Student, 2022-2024

Ph.D. Student at UC Santa Barbara

Publications

​

  • "Synthesis and Biological Evaluation of Niclosamide PROTACs", Erick Munoz, Guanglin Chen, Ahamed Hossain, Sitong Wu, Esveidy Oceguera, Jasmine Hang, Tong Lee, Qiang Zhang, Guangdi Wang*, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 72: 128870 (2022).

  • "Licochalcone A-Inspired Chalcones: Synthesis and Their
    Antiproliferative Potential in Prostate Cancer Cells",
    Roxana Gonzalez Dorado, Esveidy Isabel Oceguera Nava, Guanglin Chen, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen * Molecules, 29(24): 6023, (2024).

  • "Tetracyclic Bis-Piperidine Alkaloids: Structures, Bioinspired Synthesis, Synthesis, and Bioactivities", Stan Iridio Gómez, Esveidy Isabel Oceguera Nava, Abbas Dadawalla, Dennis Ashong, Guanglin Chen, Qiao-Hong Chen*, Molecules 30(14): 2907 (2025).

  • "Natural Products Targeting the Androgen Receptor Signaling Pathway:Therapeutic Potential and Mechanisms", Sitong Wu, Esveidy Isabel Oceguera Nava, Dennis Ashong, Guanglin Chen, Qiao-Hong Chen*, Current Issues in Molecular Biology, 47(9): 780  (2025).

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Sitong Wu

Master Graduate Student, 2019-2022

Ph.D. Student at University of California, San Diego

Publications

​

  • "3-O-Carbamoyl-5,7,20-O-trimethylsilybins: Synthesis and preliminary antiproliferative evaluation", Sitong Wu, Guanglin Chen, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Molecules, 26 (21): 6421 (2021).

  • "Synthesis and Biological Evaluation of Niclosamide PROTACs", Erick Munoz, Guanglin Chen, Ahamed Hossain, Sitong Wu, Esveidy Oceguera, Jasmine Hang, Tong Lee, Qiang Zhang, Guangdi Wang*, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 72: 128870 (2022).

  • "Core Structure-Activity Relationship Studies of 5,7,20-O-Trimethylsilybins in Prostate Cancer Cell Models", SitongWu, Guanglin Chen, Eva Y. Chen, Leyla S. Farshidpour, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Pharmaceuticals, 16: 531 (2023).

  • "Natural Products Targeting the Androgen Receptor Signaling Pathway:Therapeutic Potential and Mechanisms", Sitong Wu, Esveidy Isabel Oceguera Nava, Dennis Ashong, Guanglin Chen, Qiao-Hong Chen*, Current Issues in Molecular Biology, 47(9): 780  (2025).

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Dennis Ashong,

Master Graduate Student, 2021-2025

Ph.D. Student at Wayne State University

Publications

​

  • "Tricyclic Diterpenoids Selectively Suppress Androgen Receptor-PositiveProstate Cancer Cells", Inderpal Sekhon, Guanglin Chen, Keyara Piri, Seiji Shinkawa, Dennis Ashong, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Molecules, 28(12): 4743 (2023).

  • "Insight into recent advances in degrading androgen receptor for castration-resistant prostate cancer", Qiao-Hong Chen*, Erick Munoz, and Dennis Ashong, Cancers, 16: 663 (2024).

  • "Tetracyclic Bis-Piperidine Alkaloids: Structures, Bioinspired Synthesis, Synthesis, and Bioactivities", Stan Iridio Gómez, Esveidy Isabel Oceguera Nava, Abbas Dadawalla, Dennis Ashong, Guanglin Chen, Qiao-Hong Chen*, Molecules 30(14): 2907 (2025).

  • "Natural Products Targeting the Androgen Receptor Signaling Pathway:Therapeutic Potential and Mechanisms", Sitong Wu, Esveidy Isabel Oceguera Nava, Dennis Ashong, Guanglin Chen, Qiao-Hong Chen*, Current Issues in Molecular Biology, Current Issues in Molecular Biology, 47(9): 780 (2025).

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Roxana Gonzalez

Master Graduate Student, 2023-2025

Ph.D. Student at UC Merced

Publications

​

  • "Licochalcone A-Inspired Chalcones: Synthesis and Their
    Antiproliferative Potential in Prostate Cancer Cells",
    Roxana Gonzalez Dorado, Esveidy Isabel Oceguera Nava, Guanglin Chen, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen * Molecules, 29(24): 6023, (2024).

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Erick Munoz 

Master Graduate Student, 2020-2022

Ph.D. Student at University of California, Davis

Publications

​

  • "Synthesis and Biological Evaluation of Niclosamide PROTACs", Erick Munoz, Guanglin Chen, Ahamed Hossain, Sitong Wu, Esveidy Oceguera, Jasmine Hang, Tong Lee, Qiang Zhang, Guangdi Wang*, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 72: 128870 (2022).

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Maricarmen Gonzalez

Master Graduate Student, 2017-2019

Ph.D., The Ohio State University

Publications

​

  • "An amide mimic of desTHPdactylolide: Total synthesis and antiproliferative evaluation", Guanglin Chen, Maricarmen Gonzalez, Ziran Jiang, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 40: 127970, 2021.

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Leyla Farshidpour

Undergraduate, 2015-2017

MD, Medical School UC Davis

Publications

​

  • "Core Structure-Activity Relationship Studies of 5,7,20-O-Trimethylsilybins in Prostate Cancer Cell Models", SitongWu, Guanglin Chen, Eva Y. Chen, Leyla S. Farshidpour, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Pharmaceuticals, 16: 531 (2023).

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Alyssa Rivera

Undergraduate, 2017-2020

MD student at UCSF School of Medicine

Publications

​

  • Second-generation androgen receptor antagonists as hormonal therapeutics for three forms of prostate cancer", Pravien Rajaram, Alyssa Rivera, Kevin Muthima, Nicholas Olveda, Hubert Muchalski*, and Qiao-Hong Chen*, Molecules, 25(10): 2448 (2020).

  • "Nitrogen-containing derivatives of tetramethylquercetin: synthesis and biological profiles in prostate cancer cell models", Pravien Rajaram, Ziran Jiang, Guanglin Chen, Alyssa Rivera, Alison Phasakda, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic Chemistry, 87: 227-239 (2019).

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Tong Lee

Undergraduate, 2020-2022

PharmD Student at University of Southern California Pharmacy School

Publications

​

  • "Synthesis and Biological Evaluation of Niclosamide PROTACs", Erick Munoz, Guanglin Chen, Ahamed Hossain, Sitong Wu, Esveidy Oceguera, Jasmine Hang, Tong Lee, Qiang Zhang, Guangdi Wang*, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, accepted (2022).

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Nawras Samaan                                    

Undergraduate Student 2013-2014

MD, St Georges University School of Medicine-Grenada

Publications

​

  • ""Design, synthesis, and evaluation of novel heteroaromatic analogs of curcumin as anti-cancer agents", Nawras Samaan, Qiu Zhong, Jayjoel Fermandez, Guanglin Chen, Ali M Hussain, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 75: 123-131 (2014).

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Matthew Lansman

Undergraduate Student (2017-2018)

DO, California Health Sciences University

.

​

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  Kevin Yu

  Graduate Student, 2014-2016

  (from National Chung Cheng University, Taiwan)

Publications

​

  • "A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: design, synthesis, and anti-proliferative evaluation", Qiao-Hong Chen*, Kevin Yu, Xiaojie Zhang, Guanglin Chen, Andrew Hoover, Francisco Leon, Rubing Wang, Nithya Subrahmanyam, Ermias A Mekuria, Liva H Rakotondraibe, Bioorganic & Medicinal Chemistry Letters, 25(20): 4553-4556 (2015).

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Inderpal Sekhon

Graduate Student, 2020-2023

Lecturer, Chemistry and Biochemistry, Fresno State

Publications

​

  • "Tricyclic Diterpenoids Selectively Suppress Androgen Receptor-PositiveProstate Cancer Cells", Inderpal Sekhon, Guanglin Chen, Keyara Piri, Seiji Shinkawa, DennisAshong, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Molecules, 28(12): 4743 (2023).

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Kevin Muthima

Graduate Student, 2017-2019

Chemistry Lecturer, College Of The Sequoias

Publications

​

  • "Second-generation androgen receptor antagonists as hormonal therapeutics for three forms of prostate cancer", Pravien Rajaram, Alyssa Rivera, Kevin Muthima, Nicholas Olveda, Hubert Muchalski*, and Qiao-Hong Chen*, Molecules, 25(10): 2448 (2020).

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Timmy Lee

Undergraduate, 2015-2018

High School Teacher

Publications

​

  • "3-O-Alkyl-2,3-Dehydrosilibinins: Two Synthetic Approaches and in vitro Effects toward Prostate Cancer Cells", Sheng Zhang, Bao Vue, Michael Huang, Xiaojie Zhang, Timmy Lee, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang,  and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 26(14): 3226-3231 (2016).

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Abbas Dadawalla

Undergraduate Student, 2022-2025

Publications

​

"Tetracyclic Bis-Piperidine Alkaloids: Structures, Bioinspired Synthesis, Synthesis, and Bioactivities", Stan Iridio Gómez, Esveidy Isabel Oceguera Nava, Abbas Dadawalla, Dennis Ashong, Guanglin Chen, Qiao-Hong Chen*, Molecules 30(14): 2907 (2025).

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Michael Huang

Visiting student (2015)

BA. Rice University

MD. McGovern Medical School

Publications

​

  • "3-O-Alkyl-2,3-Dehydrosilibinins: Two Synthetic Approaches and in vitro Effects toward Prostate Cancer Cells", Sheng Zhang, Bao Vue, Michael Huang, Xiaojie Zhang, Timmy Lee, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang,  and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 26(14): 3226-3231 (2016).

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Lorena Orozco
Visiting student (2019)
(from Stanford University)

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Stephanie Santos
Undergraduate Student (2015-2016)
(Fresno State, Biology)

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Ryan C Froese
Graduate Student (2012-2015)
BS. Cal Poly SLO
Professor of Organic Chemistry · College of the Sequoias

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Johnathan Diaz
Undergraduate, 2024-2025

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Sheye Lee
Undergraduate Student (2017-2018)
PharmD, California Health Science's University
​

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Jack Vang
Undergraduate Student (2017-2018)
​PharmD Student at Western University of Health Sciences Pomona

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Jennifer Phan
Undergraduate, 2017-2019

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Irvin Vides
Undergraduate Student, 2018-2019

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 Ruby Her                                    
 Undergraduate, 2017-2018                                                      
 (Fresno State, Chemistry)        

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Nicholas Olveda

Undergraduate, 2018-2020

Publications

​

  • "Second-generation androgen receptor antagonists as hormonal therapeutics for three forms of prostate cancer", Pravien Rajaram, Alyssa Rivera, Kevin Muthima, Nicholas Olveda, Hubert Muchalski*, and Qiao-Hong Chen*, Molecules, 25(10): 2448 (2020).

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Samantha Mallory                                

Undergraduate, 2017-2018                                                       

OMS2 at Idaho College of Osteopathic Medicine    

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Nandini Nair

(High School Student), 2016    

Publications

​

  • 5- or/and 20-O-Alkyl-2,3-dehydrosilybins: Synthesis and biological profiles on prostate cancer cell models", Bao Vue, Xiaojie Zhang, Timmy Lee, Nandini Nair, Sheng Zhang, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 25(17): 4845-4854 (2017).

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Donglin(Allan) Song

High School Student, 2019-

.

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Emma Chen

High School Student, 2018-2019

.

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Rachel Lee Nelson

Undergraduate 2015-2016   

.

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Andrew Hoover

Undergraduate, 2014-2015

Publications

​

  • "A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: design, synthesis, and anti-proliferative evaluation", Qiao-Hong Chen*, Kevin Yu, Xiaojie Zhang, Guanglin Chen, Andrew Hoover, Francisco Leon, Rubing Wang, Nithya Subrahmanyam, Ermias A Mekuria, Liva H Rakotondraibe, Bioorganic & Medicinal Chemistry Letters, 25(20): 4553-4556 (2015).

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Hualia Yang                                   

Undergraduate Student 2015-2016

   

​

​

.

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Joshua Z Keith

Undergraduate 2014-2015   

Publications

​

  • "Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies", Xiaojie Zhang, Shanchun Guo, Chengsheng Chen, German Ruiz Perez, Changde Zhang, Manee Patanapongpibul, Nithya Subrahmanyam, Rubing Wang, Joshua Keith, Guanglin Chen, Yan Dong, Qiang Zhang, Qiu Zhong, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 137: 263-279 (2017).

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Ali M Hussain

Undergraduate, 2012-2013

MD., American University of the Caribbean

Publications

​

''Design, synthesis, and evaluation of novel heteroaromatic analogs of curcumin as anti-cancer agents", Nawras Samaan, Qiu Zhong, Jayjoel Fermandez, Guanglin Chen, Ali M Hussain, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 75: 123-131 (2014).

  • Nasim Ravanbakhsh Undergraduate, 2012 

  • Ceorge S Mikhail, Undergraduate, 2013

  • Yashin Manraj, Undergraduate (2013-2014)

  • Michael Putnam, Undergraduate, 2014

  • Juan Luis Villalobos, Undergraduate, 2015

  • Dainelle Rodriguez, Undergraduate, 2015

  • Harmeet K Dhalinwal, Undergraduate Student 2016

  • Tom Lor, Undergraduate, 2016

  • Justin Houts, Undergraduate Student 2018

  • Miguel Gomez, Undergraduate Student 2018

  • Zhora Pogosyan, Undergraduate, 2018 

  • Dustin Echeveria, Undergraduate Student (2017-2018)

  • Jason Le, Undergraduate Student 2018

  • Jose Gutierrez Larios, Undergraduate, 2018

  • Alison Phasakda, High School Student), 2017

  • Vinita Raj, High School Student, 2018

  • Varun Raj, High School Student, 2018

  • Hari Subramanian, High School Student, 2018

  • Vana Wassilian, Undergraduate Student, 2018-2019

  • Nagat Alrubati, Undergraduate, 2018-2022

  • Daeun Kim, High School Student, 2020

  • Ivan Gonzalez, Undergraduate, 2020

  • Calicia Dahna, Graduate Student, 2022

  • Nancy Martinez, Graduate Student, 2020-2022

  • Zhora Pogosyan, Graduate Student, 2020-2023

  • Avneet Purewal, Undergraduate, 2022-2023

  • Marvin Cornejo Callejas, Undergraduate, 2023-2024

  • Alonso Medrana-Luna, Undergraduate Student, 2023-2024

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